Noteworthy News Articles on Mental Health Topics, August 12-27, 2007 Gina Kolata, New York Times- 8/12/2007 Everyone knows men are promiscuous by nature. It’s part of the genetic strategy that evolved to help men spread their genes far and wide. The strategy is different for a woman, who has to go through so much just to have a baby and then nurture it. She is genetically programmed to want just one man who will stick with her and help raise their children. Surveys bear this out. In study after study and in country after country, men report more, often many more, sexual partners than women. One survey, recently reported by the federal government, concluded that men had a median of seven female sex partners. Women had a median of four male sex partners. Another study, by British researchers, stated that men had 12.7 heterosexual partners in their lifetimes and women had 6.5. But there is just one problem, mathematicians say. It is logically impossible for heterosexual men to have more partners on average than heterosexual women. Those survey results cannot be correct. It is about time for mathematicians to set the record straight, said David Gale, an emeritus professor of mathematics at the University of California, Berkeley. “Surveys and studies to the contrary notwithstanding, the conclusion that men have substantially more sex partners than women is not and cannot be true for purely logical reasons,” Dr. Gale said. He even provided a proof, writing in an e-mail message: “By way of dramatization, we change the context slightly and will prove what will be called the High School Prom Theorem. We suppose that on the day after the prom, each girl is asked to give the number of boys she danced with. These numbers are then added up giving a number G. The same information is then obtained from the boys, giving a number B. Theorem: G=B Proof: Both G and B are equal to C, the number of couples who danced together at the prom. Q.E.D.” Sex survey researchers say they know that Dr. Gale is correct. Men and women in a population must have roughly equal numbers of partners. So, when men report many more than women, what is going on and what is to be believed? “I have heard this question before,” said Cheryl D. Fryar, a health statistician at the National Center for Health Statistics and a lead author of the new federal report, “Drug Use and Sexual Behaviors Reported by Adults: United States, 1999-2002,” which found that men had a median of seven partners and women four. But when it comes to an explanation, she added, “I have no idea.” “This is what is reported,” Ms. Fryar said. “The reason why they report it I do not know.” Sevgi O. Aral, who is associate director for science in the division of sexually transmitted disease prevention at the Centers for Disease Control and Prevention, said there are several possible explanations and all are probably operating. One is that men are going outside the population to find partners, to prostitutes, for example, who are not part of the survey, or are having sex when they travel to other countries. Another, of course, is that men exaggerate the number of partners they have and women underestimate. Dr. Aral said she cannot determine what the true number of sex partners is for men and women, but, she added, “I would say that men have more partners on average but the difference is not as big as it seems in the numbers we are looking at.” Dr. Gale is still troubled. He said invoking women who are outside the survey population cannot begin to explain a difference of 75 percent in the number of partners, as occurred in the study saying men had seven partners and women four. Something like a prostitute effect, he said, “would be negligible.” The most likely explanation, by far, is that the numbers cannot be trusted. Ronald Graham, a professor of mathematics and computer science at the University of California, San Diego, agreed with Dr. Gale. After all, on average, men would have to have three more partners than women, raising the question of where all those extra partners might be. “Some might be imaginary,” Dr. Graham said. “Maybe two are in the man’s mind and one really exists.” Dr. Gale added that he is not just being querulous when he raises the question of logical impossibility. The problem, he said, is that when such data are published, with no asterisk next to them saying they can’t be true, they just “reinforce the stereotypes of promiscuous males and chaste females.” In fact, he added, the survey data themselves may be part of the problem. If asked, a man, believing that he should have a lot of partners, may feel compelled to exaggerate, and a woman, believing that she should have few partners, may minimize her past. “In this way,” Dr. Gale said, “the false conclusions people draw from these surveys may have a sort of self-fulfilling prophecy.” Hostility May Raise Risk for Disease Nicholas Bakalar, New York Times- 8/14/2007 Researchers studying 313 healthy Vietnam veterans have found that anger and hostility may increase the risk for cardiovascular disease, diabetes and high blood pressure. Over a period of 10 years, the men had regular physical examinations involving a wide variety of medical tests. They also underwent psychological examinations using well-established questionnaires to determine their levels of hostility, anger and depression. The researchers measured blood levels of a protein called C3, a marker for the inflammation that is a risk factor for cardiovascular illnesses. After controlling for other variables, the scientists found that those in the highest one-quarter in hostility, anger and depression showed a steady and significant increase in C3 levels, while those in the lowest onequarter had no increase. "This may put those men at increased risk for hypertension, diabetes and coronary heart disease," said Stephen H. Boyle, the lead author of the study and a researcher at Duke University Medical Center. Why these increases in C3 levels happen is unknown, but the authors speculate that anger in hostile and depressed men initiates a series of chemical responses in the immune system that lead to inflammation. Taking steps to control hostility may be helpful. "There are interventions that appear to be useful in lowering levels of anger," Dr. Boyle said. "I don't know if their long-term effects on physiology have been tested, but if you're less angry and hostile, that in itself is a worthy goal." The study was published in the August issue of Brain, Behavior and Immunity. To Reap Psychotherapy’s Benefits, Get a Good Fit Richard A. Friedman, M.D., New York Times- 8/21/2007 Americans seem to like psychotherapy. Whether it’s for the mundane conflicts of everyday life or life-threatening illnesses like major depression, psychotherapy is widely viewed as a healthy, if not harmless, pursuit. Yet unlike most other medical treatments, psychotherapy can take considerable time. An infection can be cured in days, but remission of severe depression or anxiety disorder usually takes weeks or months, and a personality disorder typically requires years of intensive psychotherapy. So if the outcome may be months or years away, how can a person tell whether his psychotherapy is any good? It’s harder than you’d think. For one thing, people commonly equate feeling better with getting good treatment. But since psychiatric disorders fluctuate spontaneously with time, like most illnesses, many patients would get better even if they got no treatment at all. A patient getting bad psychotherapy might flourish, while another patient getting exemplary treatment might suffer terribly. Judging from one of the largest surveys of psychotherapy to date, most Americans who try psychotherapy think it is beneficial. In its 1994 annual questionnaire, Consumer Reports asked readers about their experience in psychotherapy. Of 7,000 subscribers who responded to the mental health questions, 4,100 saw mental health professionals. Most reported feeling better with therapy, regardless of whether they were treated by a psychologist, a psychiatrist or a social worker. And those in long-term therapy reported more improvement than those in short-term therapy. Of course, not all therapy is helpful, and some of it can be downright harmful. Many patients have problems with relationships in the first place; they can find it difficult to extricate themselves from bad or ineffective therapy. I recall a successful writer whom I saw in consultation. At 44, he had been in psychotherapy for several years and felt that while he had gained much self-understanding, his chronically depressed mood had not changed. After seeing his depressed partner respond vividly to an antidepressant, he wondered if he too might benefit from a similar drug, but his therapist was opposed. “He told me that I would be forestalling symptoms with medication that would return years later when I stopped medication,” the writer said. He persisted and got a second opinion. “Be very wary of any therapist who discourages a consultation,” said a colleague of mine, Dr. Robert Michels, university professor of psychiatry at Weill Cornell Medical College. “If a patient is uncomfortable at the start of treatment, he should leave. But if a patient dislikes his therapy later on, he should discuss it with his therapist, and, if they can’t agree, then it’s time for a consultation. A competent therapist should welcome it.” It is hardly surprising that many patients are reluctant to seek a second opinion; they may fear rejection by their therapist, or hurting the therapist’s feelings. And therapists, having egos like everyone else, may resist an independent consultation because they see it as a sign of their own failure, not to mention the obvious financial incentive to hold on to a patient. It’s not just patients who have a hard time knowing if their treatments are helping them; sometimes the therapists themselves can’t tell. In a study published last month in the journal Psychotherapy Research, Michael J. Lambert and Cory Harmon, psychologists at Brigham Young University, gave psychotherapy patients a questionnaire about how they were feeling and functioning. They randomly gave feedback from the questionnaires to half the patients’ therapists; the other half received strengthened feedback, which included patient self-assessment plus specific information about how the patients viewed their therapists and their social supports. These two groups were compared with a control group of patients whose therapists received no feedback. The researchers found that giving feedback to therapists clearly improved treatment outcome: When therapists received no feedback, 21 percent of their patients deteriorated. With therapists who received regular feedback, 13 percent of patients deteriorated; with strengthened feedback, 7 percent of patients deteriorated. The clear implication is that therapists are not always the best judge of how their patients are doing, perhaps because they are blinded by their own optimism and determination to succeed. Some therapists might even view worsening during treatment as a sign of progress — a misguided “no pain, no gain” view of psychotherapy. It’s probably easier to say what is bad psychotherapy than what is good, but there are qualities that all good therapies share. You should feel that you are understood as an individual, and that your therapist is compassionate and nonjudgmental. Good therapists should be able to explain the nature of your problem, and which of several treatments might help you. Ask yourself not just whether you are getting better, but whether you are getting optimal treatment. Information about psychiatric disorders and recommended treatment can be found at several of reputable Web sites, including those of the American Psychiatric Association at www.psych.org, and the National Institute of Mental Health at www.nimh.nih.gov. The psychiatric association’s treatment guidelines describe what is considered state-of-the-art treatment for various disorders and the empirical basis for the recommendations; see them at www.psych.org/psych_pract. While it will not guarantee good therapy, seeing an accredited mental health professional provides some assurance of skill and competence. Feeling better is important, of course, but it is possible to feel good and be stalled, where little significant change is taking place. If you are in therapy, don’t just rely on your own feelings to judge the treatment; speak to good friends and family members and see what they think about how you’re doing. In the end, psychotherapy is a very personal business. If you need brain surgery, it doesn’t really matter if you like your surgeon as long as he’s skilled and competent. But in therapy, skill and competence are necessary but not enough; personal fit, more than almost anything, can make the therapy — or break it. Richard A. Friedman is a professor of psychiatry at Weill Cornell Medical College. Survey: Post - Storm Mental Health Worsens Associated Press, 8/21/2007 NEW ORLEANS -- More Gulf Coast residents are thinking seriously about suicide or showing symptoms of post-traumatic stress disorder as the recovery from Hurricane Katrina inches along, a new survey finds. The survey is a follow-up to one done six months after the hurricane, which found that few people in Louisiana, Mississippi and Alabama -- about 3 percent -- had contemplated suicide in the storm's aftermath. That figure has now doubled in the three-state area and is up to 8 percent in the New Orleans area, according to Ronald Kessler of Harvard Medical School, lead researcher for the Hurricane Katrina Community Advisory Group. More people also showed signs of post-traumatic stress disorder, 21 percent of those interviewed this year compared to 16 percent in the earlier survey. It's not surprising, said Karen Binder-Brynes, a New York psychologist who specializes in PTSD. ''It's a community that's in terrible distress. It's not like other things where, once everything's over, everything's getting rebuilt,'' she said. The Kessler team interviewed 1,000 people last year and was able to track down 800 of them for this year's survey. The latest survey is not yet ready for publication, but Kessler said the preliminary results for suicide and PTSD were striking. Kessler said that in the months after the Aug. 29, 2005 hurricane, an underlying optimism protected many people from suicidal thoughts. Now, that optimism has worn thin -- something the earlier report warned could happen if rebuilding didn't keep pace with expectations. The recovery from Katrina has been slow in some areas, especially in New Orleans. In addition to losses due directly to the storm, violent crime, poor schools and other problems have piled trauma atop trauma. Kessler, whose study is supported by the National Institutes of Health and the World Health Organization, said most disasters have relatively rapid recoveries, so rates for such ailments as depression and PTSD usually improve after a year. The results of the New Orleans survey are more like those of people who lost their jobs in Detroit during the 1980s and couldn't find new work, he said.
Dave Collins, Hartford Courant, 8/21/2007 WASHINGTON - Retail sales of five leading painkillers nearly doubled from 1997 to 2005, reflecting a surge in use by patients nationwide, according to an Associated Press analysis of federal drug prescription data. The amount of five major painkillers sold at retail establishments rose 90 percent during that time, according to Drug Enforcement Administration figures. More than 200,000 pounds of codeine, morphine, oxycodone, hydrocodone and meperidine were purchased at retail stores during 2005, the most recent year represented in the data. That is enough to give more than 300 milligrams of painkillers to every person in America. Oxycodone, the chemical used in OxyContin, is responsible for most of the increase. Oxycodone sales jumped nearly sixfold between 1997 and 2005. The drug gained notoriety as "hillbilly heroin," often bought and sold illegally in Appalachia. But its highest rates of sale now occur in places such as suburban St. Louis and Ft. Lauderdale. "What we're seeing now is the rest of the nation catching up to where we were," said Robert Walker, a researcher at the University of Kentucky Center on Drug and Alcohol Research. In Appalachia, retail sales of hydrocodone -- sold mostly as Vicodin -- are the highest in the nation. Nine of the 10 areas with the highest per-capita sales are in mostly rural parts of West Virginia, Kentucky or Tennessee. Less regulated than similar prescription painkillers, drugs containing hydrocodone have become the most widely prescribed opiate painkillers on the market. Steve Dotson, a southern West Virginia resident, is among millions of Americans who has experienced the harm of addiction to hydrocodone. Dotson, 43, at one point lost his house, the state took his children away and he was spending nights under a bridge, where he hoped to die. "You get to where you don't even want them pills anymore; you just do them so you can get through the day," he said. Dotson said he has been off drugs since a religious experience in 2001. Not all of his friends were so lucky, he said. "You've got three choices," he said. "You either die, go to prison or get saved. Mostly, people around here are dying." DEA figures analyzed by the AP include nationwide sales and distribution of drugs by hospitals, retail pharmacies, doctors and teaching institutions. Federal investigators study the same data trying to identify illegal prescription patterns. It is impossible to reliably measure painkiller abuse. A 2004 government study estimated between 2 million and 3 million doses of codeine, hydrocodone and oxycodone are stolen annually. The AP's analysis included only retail sales. More people are abusing prescription painkillers, experts say, because the medications are more available. Spooked by high-profile arrests and prosecutions, many pain-management specialists now say they won't write prescriptions even for the sickest people. As a result, people who desperately need strong painkillers sometimes are forced to go long distances to find doctors willing to prescribe them. Siobhan Reynolds, widow of a New Mexico patient who needed large amounts of painkillers for a connective tissue disorder, said she routinely drove her late husband to a doctor in Oklahoma. In Myrtle Beach, S.C., during the eight-year period reflected in government figures, oxycodone distribution increased 800 percent, partly due to a campaign by Purdue Pharma of Stamford, Conn. The privately held company has pleaded guilty to lying to patients, doctors and regulators about the drug's addictive nature. The U.S. attorney for South Carolina secured a 58-count indictment in June 2002 against seven physicians and an employee of the Comprehensive Care and Pain Management Center. A Myrtle Beach internist who works in addiction medicine, Brian Adler, said physicians were flooded with patients seeking pain medicine after the clinic was shut down. "There's a significant problem with narcotics in this area," Adler said. After the pain management clinic closed, "all those folks were like rats, scurrying from a burning building, trying to get their fix." Reasons for booming sales of pain medication: *Aging population -- In 2000, there were 35 million people older than 65. By 2020, that number will reach 54 million. *Unprecedented marketing -- Spending on drug marketing zoomed to nearly $30 billion in 2005 from $11 billion in 1997. *Change in pain management philosophy -- Doctors who once advised patients that pain is part of the healing process now mostly see pain management as an important factor in overcoming illness. Criticism of a Gender Theory, and a Scientist Under Siege Benedict Carey, New York Times- 8/21/2007 In academic feuds, as in war, there is no telling how far people will go once the shooting starts. Earlier this month, members of the International Academy of Sex Research, gathering for their annual meeting in Vancouver, informally discussed one of the most contentious and personal social science controversies in recent memory. The central figure, J. Michael Bailey, a psychologist at Northwestern University, has promoted a theory that his critics think is inaccurate, insulting and potentially damaging to transgender women. In the past few years, several prominent academics who are transgender have made a series of accusations against the psychologist, including that he committed ethics violations. A transgender woman he wrote about has accused him of a sexual impropriety, and Dr. Bailey has become a reviled figure for some in the gay and transgender communities. To many of Dr. Bailey’s peers, his story is a morality play about the corrosive effects of political correctness on academic freedom. Some scientists say that it has become increasingly treacherous to discuss politically sensitive issues. They point to several recent cases, like that of Helmuth Nyborg, a Danish researcher who was fired in 2006 after he caused a furor in the press by reporting a slight difference in average I.Q. test scores between the sexes. “What happened to Bailey is important, because the harassment was so extraordinarily bad and because it could happen to any researcher in the field,” said Alice Dreger, an ethics scholar and patients’ rights advocate at Northwestern who, after conducting a lengthy investigation of Dr. Bailey’s actions, has concluded that he is essentially blameless. “If we’re going to have research at all, then we’re going to have people saying unpopular things, and if this is what happens to them, then we’ve got problems not only for science but free expression itself.” To Dr. Bailey’s critics, his story is a different kind of morality tale. “Nothing we have done, I believe, and certainly nothing I have done, overstepped any boundaries of fair comment on a book and an author who stepped into the public arena with enthusiasm to deliver a false and unscientific and politically damaging opinion,” Deirdre McCloskey, a professor of economics, history, English, and communication at the University of Illinois at Chicago, and one of Dr. Bailey’s principal critics, said in an e-mail message. The hostilities began in the spring of 2003, when Dr. Bailey published a book, “The Man Who Would Be Queen,” intended to explain the biology of sexual orientation and gender to a general audience. “The next two years,” Dr. Bailey said in an interview, “were the hardest of my life.” Many sex researchers who have worked with Dr. Bailey say that he is a solid scientist and collaborator, who by his own admission enjoys violating intellectual taboos. In his book, he argued that some people born male who want to cross genders are driven primarily by an erotic fascination with themselves as women. This idea runs counter to the belief, held by many men who decide to live as women, that they are the victims of a biological mistake — in essence, women trapped in men’s bodies. Dr. Bailey described the alternate theory, which is based on Canadian studies done in the 1980s and 1990s, in part by telling the stories of several transgender women he met through a mutual acquaintance. In the book, he gave them pseudonyms, like “Alma” and “Juanita.” Other scientists praised the book as a compelling explanation of the science. The Lambda Literary Foundation, an organization that promotes gay, bisexual and transgender literature, nominated the book for an award. But days after the book appeared, Lynn Conway, a prominent computer scientist at the University of Michigan, sent out an e-mail message comparing Dr. Bailey’s views to Nazi propaganda. She and other transgender women found the tone of the book abusive, and the theory of motivation it presented to be a recipe for further discrimination. Dr. Conway did not respond to requests for an interview. Dr. Ben Barres, a neurobiologist at Stanford, said in reference to Dr. Bailey’s thesis in the book, “Bailey seems to make a living by claiming that the things people hold most deeply true are not true.” At a public meeting of sex researchers shortly after the book’s publication, Dr. John Bancroft, then director of the Kinsey Institute for Research in Sex, Gender and Reproduction, said to Dr. Bailey, “Michael, I have read your book, and I do not think it is science,” according to accounts of the meeting. Dr. Bancroft confirmed the comment. After consulting with Dr. Conway, four of the transgender women who spoke to Dr. Bailey during his reporting for the book wrote letters to Northwestern, complaining that they had been used as research subjects without having given, or been asked to sign, written consent. One wrote a letter making another accusation against Dr. Bailey: she claimed he had had sex with her. Dr. Conway and Dr. McCloskey also wrote letters to Northwestern, accusing Dr. Bailey of grossly violating scientific standards “by conducting intimate research observations on human subjects without telling them that they were objects of the study.” They also wrote to the Illinois state regulators, requesting that they investigate Dr. Bailey for practicing psychology without a license. Dr. Bailey, who was not licensed to practice clinical psychology in Illinois, had provided some of those who helped him with the book with brief case evaluation letters, suggesting that they were good candidates for sex-reassignment surgery. A spokesman for the state said that regulators took no action on the complaints. In an interview, Dr. Bailey said that nothing he did was wrong or unethical. “I interviewed people for a book,” he said. “This is a free society, and that should be allowed.” But by the end of 2003, the controversy had a life of its own on the Internet. Dr. Conway, the computer scientist, kept a running chronicle of the accusations against Dr. Bailey on her Web site. Any Google search of Dr. Bailey’s name brought up Dr. Conway’s site near the top of the list. The site also included a link to the Web page of another critic of Dr. Bailey’s book, Andrea James, a Los Angeles-based transgender advocate and consultant. Ms. James downloaded images from Dr. Bailey’s Web site of his children, taken when they were in middle and elementary school, and posted them on her own site, with sexually explicit captions that she provided. (Dr. Bailey is a divorced father of two.) Ms. James said in an e-mail message that Dr. Bailey’s work exploited vulnerable people, especially children, and that her response echoed his disrespect. Dr. Dreger is the latest to arrive at the battlefront. She is a longtime advocate for people born with ambiguous sexuality and has been strongly critical of sex researchers in the past. She said she had presumed that Dr. Bailey was guilty and, after meeting him through a mutual friend, had decided to investigate for herself. But in her just-completed account, due to be published next year in The Archives of Sexual Behavior, the field’s premier journal, she concluded that the accusations against the psychologist were essentially groundless. For example, Dr. Dreger found that two of the four women who complained to Northwestern of research violations were not portrayed in the book at all. The two others did know their stories would be used, as they themselves said in their letters to Northwestern. The accusation of sexual misconduct came five years after the fact, and was not possible to refute or confirm, Dr. Dreger said. It specified a date in 1998 when Dr. Bailey was at his ex-wife’s house, looking after their children, according to dated e-mail messages between the psychologist and his ex-wife, Dr. Dreger found. The transgender woman who made the complaint said through a friend that she stood by the accusation but did not want to talk about it. Moreover, based on her own reading of federal regulations, Dr. Dreger, whose report can be viewed at www.bioethics.northwestern.edu, argued that the book did not qualify as scientific research. The federal definition describes “a systematic investigation, including research development, testing and evaluation.” Dr. Bailey used the people in his book as anecdotes, not as the subjects of a systematic investigation, she reported. “The bottom line is that they tried to ruin this guy, and they almost succeeded,” Dr. Dreger said. Dr. Dreger’s report began to circulate online last week, and Dr. Bailey’s critics already have attacked it as being biased. For their part, Northwestern University administrators began an investigation of Dr. Bailey’s research in later 2003 (there is no evidence that they investigated the sex complaint). The inquiry, which lasted almost a year, brought research to a near standstill in Dr. Bailey’s laboratory, and clouded his name among some other researchers, according to people who worked with the psychologist. “That was the worst blow of all, that we didn’t get much support” from Northwestern, said Gerulf Rieger, a graduate student of Dr. Bailey’s at the time, and now a lecturer at Northwestern. “They were quite scared and not very professional, I thought.” A spokesman for the university declined to comment on the investigation, which concluded in 2004. One collaborator broke with Dr. Bailey over the controversy, Dr. Bailey said. Others who remained loyal said doing so had a cost: two researchers said they were advised by a government grant officer that they should distance themselves from Dr. Bailey to improve their chances of receiving financing. “He told me it would be better if I played down any association with Bailey,” said Khytam Dawood, a psychologist at Pennsylvania State University. Dr. Bailey said that the first weeks of the backlash were the worst. He tried not to think about the accusations, he said, but would wake up in the middle of the night unable to think of anything else. He took anti-anxiety pills for a while. He began to worry about losing his job. He said that friends and family supported him but that some colleagues were afraid to speak up in his defense. “They saw what I was going through, I think, and wanted no part of it,” he said. The fog of war, which can overwhelm the senses of real soldiers, can also descend on academic feuds, and it seems to have done so on this one. In October 2004, Dr. Bailey stepped down as chairman of the psychology department. He declined to say why, and a spokesman for Northwestern would say only that the change in status had nothing to do with the book. These unknowns seem if anything to have extended the life of the controversy, which still simmers online. “I think for me, for the work I do, honestly, I don’t really care what his theories are,” said Mara Keisling, executive director of the National Center for Transgender Equality, of Dr. Bailey. “But I do want to feel like any theories that affect the lives of so many people are based in good science, and that they’re presented responsibly.” But that, say supporters of Dr. Bailey, is precisely the problem: Who defines responsible? And at what cost is that definition violated? It is perhaps fitting that the history of this conflict, which caught fire online, is being written and revised continually in the online encyclopedia Wikipedia, which is compiled and corrected by users. The reference site provides a lengthy entry on Dr. Bailey, but a section titled “Research Misconduct,” which posts some of the accusations Dr. Dreger reviewed, includes a prominent warning. It reads: “The neutrality of this section is disputed.” Doctor Charged in Autistic Boy's Death Associated Press, 8/22/2007 PITTSBURGH -- A doctor was charged with involuntary manslaughter Wednesday for administering a chemical treatment that state police say killed a 5-year-old autistic boy. The child, Abubakar Tariq Nadama, went into cardiac arrest at Dr. Roy E. Kerry's office immediately after undergoing chelation therapy on Aug. 23, 2005. Chelation removes heavy metals from the body and is approved by the Food and Drug Administration for treating acute heavy metal poisoning, but not for treating autism. Some people who believe autism is caused by a mercury-containing preservative once used in vaccines say chelation may also help autistic children. The boy's parents had moved from England to the Pittsburgh area to seek treatment for his autism. They have filed a wrongful death suit against Kerry, and the state is trying to revoke his license. The state police asked Kerry to turn himself in by Thursday afternoon or risk arrest, said prosecutor Randa Clark. Police also charged Kerry with endangering the welfare of a child and reckless endangerment. Investigators, who have worked on the case for nearly two years, talked to several doctors about his methods, and one is prepared to testify that Kerry's treatment constituted gross negligence, she said. The Department of State, which licenses physicians, filed six disciplinary charges in September against Kerry. The department contends Kerry used the wrong formula of the drug and prescribed an IV push -- meaning the drugs are administered in one dose intravenously -- despite warnings that it could be lethal. The Centers for Disease Control and Prevention found that the boy was given a synthetic amino acid to rid his body of heavy metals, instead of a similar chemical with a calcium additive. Both are odorless, colorless liquids and may have been confused, the CDC found. The additive is used to replenish calcium, the loss of which can cause sudden cardiac arrest. Kerry, 69, has not commented publicly on the allegations but has defended his treatment in documents. He has argued that the boy's autism symptoms improved after the first two treatments earlier in summer 2005. Kerry acknowledged there may have been ''miscommunication'' about which medication to give the boy during the third treatment, but says that did not amount to repeated or gross negligence. A receptionist at one of Kerry's offices said the doctor was treating patients and was not immediately available for comment Wednesday. The attorney for Mawra and Rufai Nadama, John Gismondi, said criminal charges are rarely filed in disputes over medical treatment. ''Most medical situations don't involve criminal charges,'' he said. ''They may involve civil litigation, but I think criminal charges are warranted, and I think the state of Pennsylvania obviously agrees.'' Kerry could face prison time if convicted of all counts. Because he has no prior convictions, however, he is unlikely to face the maximum sentence of decades in prison, Clark said.
Associated Press, 8/22/2007 WASHINGTON -- The Food and Drug Administration on Wednesday approved a widely used adult psychiatric drug for the treatment of schizophrenia and bipolar disorder in children and adolescents. The action permits use of Risperdal for schizophrenia in youths aged 13 to 17 and for bipolar disorder in those aged 10 to 17, FDA said. It was approved last fall for treatment of irritability in autism. Risperdal, manufactured by Janssen, L.P. of Titusville, N.J., is the No. 3 anti-psychotic drug, with $2.3 billion in sales in 2005, according to the pharmaceutical data company IMS Health. Janssen is a unit of Johnson & Johnson. Risperdal was approved for use in adults in 1993. Until now, FDA said, there has been no approved drug for the treatment of schizophrenia in youths and only lithium is approved for the treatment of bipolar disorder in adolescents. The dose approved for youths is slightly lower than the adult dose, FDA said. Drowsiness, fatigue, increase in appetite, anxiety, nausea, dizziness, dry mouth, tremor, and rash were among the most common side effects reported, the agency said. On the Net: Food and Drug Administration: http://www.fda.gov
The disorder made Cho unable to speak in social settings and was deemed an emotional disability, the sources said. When he stopped getting the help that Fairfax was providing, Cho became even more isolated and suffered severe ridicule during his four years at Virginia Tech, experts suggested. In his senior year, Cho killed 32 students and faculty members and himself in the deadliest shooting by an individual in U.S. history. The condition, called selective mutism, is a symptom of a larger social anxiety disorder. It prompted the Fairfax school system to develop a detailed special education plan to help ease Cho's fears so he might begin to talk more openly, the sources said. Part of his individualized program in Fairfax excused Cho from participating in class discussions, according to the sources, who spoke on condition of anonymity because of the confidentiality of Cho's records. Another part of the plan called for private therapy to resolve his underlying anxiety. The therapy and special provisions were "apparently effective," the sources said. But once Cho left the safe and highly structured high school setting that had created a cocoon of support, officials at Virginia Tech were never told of his condition and never addressed the issue, the sources said. Since the April 16 shootings, stories have emerged from Cho's teachers and classmates at Virginia Tech. They say it was common for professors to call on Cho and for him to remain silent. The teachers would become angry, and students would taunt him. The severely isolated Cho began to refer to himself as "?". All of this would have worsened his deep-seated anxiety, experts said. "Think of the image of the little kid at the end of the diving board, just frozen. They can't move no matter how much we tell them to jump," said Robert Schum, a clinical psychologist and expert in selective mutism. "In a classroom, they feel threatened. They're trapped. And the more people push, the more it exacerbates the anxiety." Professors and school administrators at Virginia Tech could not have known of Cho's emotional disability -- Fairfax officials were forbidden from telling them. Federal privacy and disability laws prohibit high schools from sharing with colleges private information such as a student's special education coding or disability, according to high school and college guidance and admissions officials. Those laws also prohibit colleges from asking for such information. The only way Virginia Tech officials would have known about Cho's anxiety and selective mutism would have been if Cho or his parents told them about it and asked for accommodations to help him, as he had received in Fairfax. Cho's disability was first reported in the Wall Street Journal and will be explored further when a panel appointed by Gov. Timothy M. Kaine (D) releases an investigative report about the shootings. Although the only way college officials could have known about Cho's problem would have been from Cho, experts said that asking for help is an almost impossible task for someone with selective mutism. "Children with selective mutism don't want to be the center of attention. They don't like to sit on Santa's lap. They don't like their photo taken on picture day. They don't want kids to sing to them at their birthday celebration. They just want to be left alone," Schum said. "So when you put the responsibility on them and ask them to draw attention to themselves by asking for help . . . that's really tough." Cho's parents, although cooperative with Fairfax school officials, might not have fully understood what was wrong and that their son needed help in college as well. As recently as last summer, Cho's mother had sought out members of One Mind Church in Woodbridge to purge him of what the pastor there called the "demonic power" possessing him. Cho's family said he was always a quiet, reserved child. After he emigrated with his parents from South Korea when he was 8, a great-aunt in Korea said the boy's mother told her he had autism. "We knew something was wrong," the aunt, Kim Yang Soon, said in April. Classmates from Stone Middle School in Centreville remember some students making fun of Cho and his silence. "He never tried to say anything," former classmate Sam Linton said. "Even when the teachers called roll, he wouldn't say 'Present' or raise his hand. He just looked straight ahead. Someone else would have to say 'Seung's here.' " By the time Cho entered Westfield High School in Chantilly, classmate Chris Davids remembers an uncomfortable sophomore English class. Students were taking turns reading aloud from works of Shakespeare. When it was Cho's turn, he sat in silence. The teacher began to cajole him. Silence. Students began to snicker. The teacher became angry. Silence. She threatened him with an F. Finally, Cho began to read in a strange mumble. "That snickering turned to full-out laughing," Davids said. "There were several comments made, such as 'Go Back to ESL' -- English as a Second Language class -- 'Learn how to read,' or 'Go back to China.' " Not long after that incident, Fairfax school officials realized that Cho was not merely painfully shy. Nor was he being recalcitrant or passive-aggressive. He was literally too paralyzed to speak. They put him in special education and devised a number of accommodations to help him, sources said. School officials said Cho would no longer be required to answer teachers' questions or participate in classroom discussions. Davids said that he does not recall Cho ever being called on after that incident. Cho was also given speech therapy. His parents were encouraged to put him in private counseling, which they did. School officials suggested that Cho join school clubs. He joined the band, where students soon began referring to him derisively as "trombone boy." He also joined the science club. Davids, another member of the science club, said that although Cho came to many of the club's meetings and hung out, he never spoke. "The teacher who was the sponsor for the club would ask him if he wanted to participate in whatever we were doing, then leave him alone," Davids said. "If he wanted to participate, he would come over and do so; otherwise, he would just sit at a desk and stare at the desk." Although most students are given special education services because their disability makes it more difficult for them to do well academically, that is generally not the case with selective mutism, Schum said. Indeed, classmates remember Cho as intelligent and capable of getting good grades. Fairfax school officials would not speak about Cho directly, citing privacy laws. They said, however, that a team of psychologists had studied selective mutism in detail, worked with several children and felt it had made "significant progress" with the students. Ellie Barnes, director of student services for the Fairfax schools, said the best treatment for the disorder includes private counseling to unearth the emotional issues or anxiety that is causing it. The county complements that with "desensitization therapy," exposing children to their phobia in small increments "so they can understand the irrationalization of that phobia." But none of that care and level of detail was transferred to Virginia Tech. Richard Crowley, coordinator of guidance services for Fairfax, said high schools generally send transcripts to colleges with only a student's courses, grades and test scores. Race, sex, religion and even the number of times a student has been suspended are considered optional pieces of information that a student can choose to disclose. The only way college officials could tell if a student had been in special education would be by looking at the classes the student took. Basic Skills is a fairly common special education class."We don't send anything that has to do with special education," Crowley said. "If the parent, who has the authority, wants us to disclose to colleges that the student was in a special-ed program, we can do that and send whatever records they want. But that doesn't happen very often." The reason, explained Barmak Nassirian, with the American Association of Collegiate Registrars and Admissions Officers, is that in the competitive admissions process, students don't want to be at a disadvantage. As recently as 2003, parental pressure caused the College Board to stop flagging SAT scores for students who had been given special education accommodations while taking the test. Moreover, many colleges say they don't want to know because of the potential liability. "In soliciting a student's history of psychiatric treatment or diagnoses by treating physicians, you basically open a Pandora's box," Nassirian said. "Even if you should decide, for reasons that have nothing to do with medical circumstances, not to accept a student, you most certainly will have a case that will be litigated." For students who are accepted and disclose their disability, most colleges and universities have services to provide appropriate accommodations, said Andrew Flagel, dean of admissions at George Mason University. Schum said selective mutism, which can be treated successfully, had never been associated with violent behavior. Most of the children, teens and young adults who suffer from the disorder -- about 1 percent of the U.S. population -- are simply born that way. They come from families where anxieties tend to run high. One technique Schum said he has found particularly effective in helping children overcome their mutism is videotaping. Children can be videotaped reading aloud at home and then can take the tape to their teacher to be graded. Or the student can be videotaped giving a show-and-tell presentation to share with the class. So Schum was not at all surprised when the world finally heard Cho speak in a setting of his choosing, on the strange and violent tape he sent to NBC News. "He was not autistic. He clearly had the capability of talking to people," Schum said. "We saw that on the video."
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